Endocrine Abstracts

Introduction: Hypothyroidism (HypoT)-related polyneuropathy is reported to range between 42 to 72%. However, there is paucity of information regarding the prevalence and clinical course of small fibre neuropathy in HypoT. This prospective study examines small fibre function (SFF) – using the Laser doppler imager flare (LDIFLARE) technique – and structure (SFS) using in-vitro corneal confocal microscopy (IVCCM) in a cohort of HypoT subjects before ...

Acute Treatment-Induced Diabetic Neuropathy (ATDN) is a reversible small nerve fibre neuropathy involving pain and autonomic nerves precipitated by a rapid improvement in glycaemia. It is well described in adults with type 1 and 2 diabetes, but not in children. A 15 year old boy developed ATDN shortly after starting treatment for type 1 diabetes. He presented with polyuria and polydipsia and a blood glucose of 51.4 mmol/L. He was started on a basal bolus regime. Eight weeks la...